硝苯地平缓释片联合常规控糖方案治疗高血压合并2型糖尿病的疗效观察

作者单位:1.300222 天津,天津市河西区陈塘庄街社区卫生服务中心全科医学科;2.天津市武清区中医医院心血管科

 高血压;合并症;2型糖尿病;药物治疗;硝苯地平;疗效

Effect of Nifedipine Sustained Release Tablets Combined with Routine Sugar Control Regimen on Hypertension Complicated with Type 2 Diabetes Mellitus
HAN Yue1, Li Fuyue2

(1.Department of General Medicine, Hexi District Chentangzhuang Street Community Health Service Center of Tianjin, Tianjin 300222, China; 2.Department of Cardiovascular Medicine, Wuqing District Hospital of Traditional Chinese Medicine of Tianjin)

 Hypertension; Complications; Type 2 Diabetes Mellitus; Drug Treatment; Nifedipine Sustained-release Tablets; Glycemic Control Program

DOI: 10.3969/j.issn.1672-7185.2020.02.017

备注

 目的  观察硝苯地平缓释片联合常规控糖方案治疗高血压合并2型糖尿病的疗效。方法  选取2015年6月—2018年6月天津市河西区陈塘庄街社区卫生服务中心收治的120例高血压合并2型糖尿病患者,随机分为观察组和对照组各60例。对照组给予缬沙坦联合常规控糖方案,观察组给予硝苯地平缓释片联合常规控糖方案,比较两组血压、血糖指标改善程度、临床效果及不良反应发生情况。结果  观察组血压、血糖指标改善情况及治疗效果均优于对照组,差异有统计学意义(P<0.05)。两组不良反应发生情况差异无统计学意义(P>0.05)。结论  硝苯地平缓释片联合常规控糖方案治疗高血压合并2型糖尿病安全有效,值得推广。
 Objective  To observe the effect of nifedipine sustained-release tablets combined with routine glycemic control regimen in the treatment of hypertension with type 2 diabetes mellitus. Methods  A total of 120 patients with hypertension and type 2 diabetes mellitus admitted to our hospital from June 2015 to June 2018 were randomly divided into observation group and control group. The control group (60 cases) was given valsartan combined with routine glycemic control program, and the observation group (60 cases) was given nifedipine sustained-release tablets combined with routine glycemic control program. The improvement of blood pressure, blood sugar index, clinical effect and adverse reactions were compared between the two groups. Results  The improvement of blood pressure, blood sugar index and clinical efficacy in the observation group were significantly better than those in the control group (P<0.05), and there was no significant difference in adverse reactions between the two groups (P>0.05). Conclusion  Nifedipine sustained-release tablets combined with routine glycemic control regimen is effective, safe and reliable in the treatment of hypertension with type 2 diabetes mellitus, and has high application value.