[1]高峰 杨卓.莫沙必利对功能性消化不良患者胃排空及近端胃舒张能力影响[J].中国实用乡村医生杂志,2019,26(12):54-56.[doi:10.3969/j.issn.1672-7185.2019.12.018 ]
 GAO Feng,YANG Zhuo.Effect of Mosapride on Gastric Emptying and Proximal Gastric Diastolic Ability in Patients with Functional Dyspepsia[J].Chinese Practical Journal of Rural Doctor,2019,26(12):54-56.[doi:10.3969/j.issn.1672-7185.2019.12.018 ]
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莫沙必利对功能性消化不良患者胃排空及近端胃舒张能力影响()
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《中国实用乡村医生杂志》[ISSN:1672-7185/CN:21-1502/R]

卷:
26
期数:
2019年12期
页码:
54-56
栏目:
论著
出版日期:
2019-12-15

文章信息/Info

Title:
Effect of Mosapride on Gastric Emptying and Proximal Gastric Diastolic Ability in Patients with Functional Dyspepsia
文章编号:
 1672-7185(2019)12-0054-03 
作者:
高峰 杨卓
作者单位:110000 沈阳,北部战区总医院
Author(s):
GAO Feng YANG Zhuo
(Northern Theater General Hospital, Shenyang 110000, Liaoning Province, China)
关键词:
 消化不良功能性莫沙必利多潘立酮
Keywords:
Dyspepsia Functional Mosapride Domperidone Stomach
分类号:
 R57 
DOI:
10.3969/j.issn.1672-7185.2019.12.018
文献标志码:
 A
摘要:
 目的 从胃排空及近端胃舒张两方面评价莫沙必利对功能性消化不良( FD)的治疗效果。方法 收集北部战区总医院2016—2019年收治的FD患者80例,随机分为对照组和观察组各40例。对照组采用多潘立酮进行治疗,观察组采用莫沙必利进行治疗,比较两组胃排空(胃残留气体量和胃排空率)及近端胃舒张(近端胃容积)改善情况。结果 治疗前,两组胃残留气体量和胃排空率差异均无统计学意义(P>0.05);治疗后,两组胃残留气体量和胃排空率均获得改善,与治疗前相比差异有统计学意义(P<0.05),而组间差异也有统计学意义(P<0.05)。治疗0 min,两组近端胃容积差异均无统计学意义(P>0.05);治疗10 min、30 min、60 min,两组近端胃容积均获得改善,与治疗前相比差异有统计学意义(P<0.05),而组间差异也有统计学意义(P<0.05)。结论 莫沙必利能够显著改善FD患者的胃排空及近端胃舒张能力,值得临床推广应用。
Abstract:
Objective To evaluate the therapeutic effect of mosapride on gastric emptying and proximal gastric diastolic ability in patients with functional dyspepsia (FD). Methods A total of 80 FD patients admitted to our hospital from 2016 to 2019 were randomly divided into control group and observation group. The control group was treated with domperidone and the observation group was treated with mosapride. The improvement of gastric emptying (residual gas volume and gastric emptying rate) and proximal gastric relaxation (proximal gastric volume) were compared between the two groups. Results Before treatment, there was no significant difference in residual gas volume and gastric emptying rate between the two groups (P>0.05); after treatment, the gastric emptying significantly improved in each group (P<0.05), and there was also significant difference between the two groups (P<0.05). There was no significant difference in proximal gastric volume between the two groups after 0 min treatment (P>0.05); after 10 min, 30 min and 60 min treatment, proximal gastric volume in each group improved significantly compared with that before treatment (P<0.05), and the difference between the two groups was also significant (P<0.05). Conclusion Mosapride can significantly improve gastric emptying and proximal gastric diastolic capacity in FD patients, which is worthy of clinical application.

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备注/Memo

备注/Memo:
收稿日期:2019-09-21)
【通信作者】 杨卓,Email:541435770@qq.com

更新日期/Last Update: 2019-12-31